ARG67276
anti-Nmnat1 / NMNAT antibody
anti-Nmnat1 / NMNAT antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Nmnat1 / NMNAT |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Specificity | This antibody detects endogenous levels of Nmnat1 / NMNAT at Human and Mouse. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Nmnat1 / NMNAT |
| Antigen Species | Human |
| Immunogen | Synthetic peptide of human Nmnat1 / NMNAT. |
| Conjugation | Un-conjugated |
| Alternate Names | NMNAT1; Nicotinamide Nucleotide Adenylyltransferase 1; NMNAT; Nicotinamide/Nicotinic Acid Mononucleotide Adenylyltransferase 1; PNAT1; Nicotinate-Nucleotide Adenylyltransferase 1; NMN/NaMN Adenylyltransferase 1; NaMN Adenylyltransferase 1; NMN Adenylyltransferase 1; LCA9; Nicotinamide Mononucleotide Adenylyltransferase 1; Nicotinamide-Nucleotide Adenylyltransferase 1; Nicotinamide Nucleotide Adenylyltransferase; Pyridine Nucleotide Adenylyltransferase 1; Leber'S Congenital Amaurosis 9; Leber Congenital Amaurosis 9; EC 2.7.7.18; EC 2.7.7.1; SHILCA |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS, 0.02% sodium azide, 50% glycerol and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9EPA7 Mouse Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 Swiss-port # Q9HAN9 Human Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 |
|---|---|
| Gene Symbol | NMNAT1 |
| Gene Full Name | Nicotinamide Nucleotide Adenylyltransferase 1 |
| Background | This gene encodes an enzyme which catalyzes a key step in the biosynthesis of nicotinamide adenine dinucleotide (NAD). The encoded enzyme is one of several nicotinamide nucleotide adenylyltransferases, and is specifically localized to the cell nucleus. Activity of this protein leads to the activation of a nuclear deacetylase that functions in the protection of damaged neurons. Mutations in this gene have been associated with Leber congenital amaurosis 9. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on chromosomes 1, 3, 4, 14, and 15. [provided by RefSeq, Jul 2014] |
| Function | Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 32 kDa |
| PTM | Phosphoprotein. [UniProt] |
