ARG54130

anti-Noggin antibody

anti-Noggin antibody for Western blot,ICC/IF and Human

Controls and Markers antibody; Developmental Biology antibody; Signaling Transduction antibody

Overview

Product Description Mouse Monoclonal antibody recognizes NOG
Tested Reactivity Hu
Tested Application ICC/IF, WB
Specificity ARG54130 Noggin antibody [1D2-G8-G1] recognize overexpressing Noggin protein by WB and ICC/IF analysis.
Host Mouse
Clonality Monoclonal
Isotype IgG3
Target Name Noggin
Antigen Species Human
Immunogen Purified recombinant human Noggin protein fragments expressed in E.coli.
Conjugation Un-conjugated
Alternate Names SYM1; Noggin; SYNS1

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:100
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size 26 kDa

Properties

Form Liquid
Buffer Ascites
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 9241 Human NOG

Swiss-port # Q13253 Human Noggin

Gene Symbol NOG
Gene Full Name noggin
Background Essential for cartilage morphogenesis and joint formation.Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.
Function Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. Essential for cartilage morphogenesis and joint formation. Inhibits chondrocyte differentiation through its interaction with GDF5 (PubMed:21976273). [UniProt]
Cellular Localization Secreted.
Research Area Controls and Markers antibody; Developmental Biology antibody; Signaling Transduction antibody
Calculated MW 26 kDa

Images (2) Click the Picture to Zoom In

  • ARG54130 anti-Noggin antibody ICC/IF image

    Immunofluorescence: HeLa cells surface-expressing Noggin-PDGFR transmembrane domain fused protein stained with ARG54130 anti-Noggin antibody at 1:100 dilution.

  • ARG54130 anti-Noggin antibody WB image

    Western blot: CHO-K1 transfected by Noggin and stained with ARG54130 anti-Noggin antibody at 1:1000 dilution.