ARG45682
anti-ORP8 antibody
anti-ORP8 antibody for Flow cytometry,ICC/IF,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ORP8 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ORP8 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human ORP8. |
| Conjugation | Un-conjugated |
| Alternate Names | OSBPL8; Oxysterol Binding Protein Like 8; OSBP10; ORP8; MSTP120; MST120; Oxysterol-Binding Protein-Related Protein 8; OSBP-Related Protein 8; Oxysterol Binding Protein-Like 8; KIAA1451; ORP-8 |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9BZF1 Human Oxysterol-binding protein-related protein 8 |
|---|---|
| Gene Symbol | OSBPL8 |
| Gene Full Name | Oxysterol Binding Protein Like 8 |
| Background | This gene encodes a member of a family of proteins containing an N-terminal pleckstrin homology domain and a highly conserved C-terminal oxysterol-binding protein-like sterol-binding domain. It binds mutliple lipid-containing molecules, including phosphatidylserine, phosphatidylinositol 4-phosphate (PI4P) and oxysterol, and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
| Function | Lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane: specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum. Binds phosphatidylserine and PI4P in a mutually exclusive manner. [UniProt] |
| Cellular Localization | Endoplasmic reticulum; Membrane; Nucleus. [UniProt] |
| Calculated MW | 101 kDa |
| PTM | Acetylation; Phosphoprotein. [UniProt] |
Images (3) Click the Picture to Zoom In
-
ARG45682 anti-ORP8 antibody ICC/IF image
Immunofluorescence: Hela stained with ARG45682 anti-ORP8 antibody at 5 μg/ml dilution.
-
ARG45682 anti-ORP8 antibody WB image
Western blot: 293T stained with ARG45682 anti-ORP8 antibody at 0.5 μg/ml dilution.
-
ARG45682 anti-ORP8 antibody FACS image
Flow Cytometry: HepG2 stained with ARG45682 anti-ORP8 antibody at 1 µg/10^6 cells dilution.
