ARG45618
anti-OS9 antibody
anti-OS9 antibody for ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes OS9 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | OS9 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human OS9. |
| Conjugation | Un-conjugated |
| Alternate Names | OS9; OS9 Endoplasmic Reticulum Lectin; ERLEC2; OS-9; Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin; Endoplasmic Reticulum Lectin 2; Amplified In Osteosarcoma 9; Protein OS-9; Erlectin 2; Osteosarcoma Amplified 9, Endoplasmic Reticulum Associated Protein |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | OS9 |
| Gene Full Name | OS9 Endoplasmic Reticulum Lectin |
| Background | This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| Function | Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4. [UniProt] |
| Cellular Localization | Endoplasmic reticulum. [UniProt] |
| Calculated MW | 76 kDa |
| PTM | Disulfide bond; Glycoprotein. [UniProt] |
Images (4) Click the Picture to Zoom In
-
ARG45618 anti-OS9 antibody ICC/IF image
Immunofluorescence: SiHa stained with ARG45618 anti-OS9 antibody at 5 μg/ml dilution.
-
ARG45618 anti-OS9 antibody WB image
Western blot: Hela stained with ARG45618 anti-OS9 antibody at 0.5 μg/ml dilution.
-
ARG45618 anti-OS9 antibody WB image
Western blot: Rat pancreas stained with ARG45618 anti-OS9 antibody at 0.5 μg/ml dilution.
-
ARG45618 anti-OS9 antibody WB image
Western blot: Mouse pancreas stained with ARG45618 anti-OS9 antibody at 0.5 μg/ml dilution.
