ARG52379

anti-Olig 1 antibody

anti-Olig 1 antibody for Western blot,Immunohistochemistry,Immunoprecipitation and Mouse,Rat

Neuroscience antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes Olig 1
Tested Reactivity Ms, Rat
Tested Application IHC, IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Olig 1
Antigen Species Mouse
Immunogen Recombinant mouse Olig1
Conjugation Un-conjugated
Alternate Names Class E basic helix-loop-helix protein 21; Oligo1; Class B basic helix-loop-helix protein 6; BHLHE21; bHLHe21; bHLHb6; BHLHB6; Oligodendrocyte transcription factor 1

Application Instructions

Application Suggestion
Tested Application Dilution
IHC1:1000
IP1:50
WB1:3,000
Application Note Specific for the ~27 kDa Olig1 protein in Western blots. The antibody also works well for immunohistochemistry, immunocytochemistry and immunoprecipitation.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein A purified
Buffer 100 mM Glycine (pH 8.0), 200 mM Tris
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 50914 Mouse OLIG1

GeneID: 60394 Rat OLIG1

Swiss-port # Q9JKN5 Mouse Oligodendrocyte transcription factor 1

Swiss-port # Q9WUQ3 Rat Oligodendrocyte transcription factor 1

Gene Symbol OLIG1
Gene Full Name oligodendrocyte transcription factor 1
Background Olig genes have been identified as the earliest known markers of oligodendrocyte lineage determination to date (Zhou et al., 2000). Olig1 is a transcription factor which promotes formation and maturation of oligodendrocytes, especially within the brain. It is expressed in the ventral spinal cord as early as 9.5 dpc and by 15.5 dpc, olig1 is dispersed throughout the gray matter. In the postnatal brain, it is present preferentially in the white matter, such as corpus callosum and cerebellar medulla. Olig1 has been demonstrated as necessary in the repair of brain lesions in patients with multiple sclerosis (Arnett et al. 2004).
Research Area Neuroscience antibody
Calculated MW 28 kDa

Images (1) Click the Picture to Zoom In

  • ARG52379 anti-Olig 1 antibody WB image

    Western blot: neonatal Rat brain lysate showing specific immunolabeling of the ~ 27k Olig1 protein stained with ARG52379 anti-Olig 1 antibody.