ARG45813
anti-P Cadherin antibody
anti-P Cadherin antibody for Flow cytometry,ICC/IF,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes P Cadherin |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | P Cadherin |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human P Cadherin. |
| Conjugation | Un-conjugated |
| Alternate Names | CDH3; cadherin 3, type 1, P-cadherin (placental); PCAD; Cadherin-3; P-cadherin; HJMD; Placental cadherin; CDHP |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 120 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CDH3 |
| Gene Full Name | cadherin 3, type 1, P-cadherin (placental) |
| Background | This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. [provided by RefSeq, Jul 2008] |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. [UniProt] |
| Cellular Localization | Cell membrane; ; Membrane. [UniProt] |
| Calculated MW | 91 kDa |
| PTM | Glycoprotein. [UniProt] |
Images (3) Click the Picture to Zoom In
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ARG45813 anti-P Cadherin antibody ICC/IF image
Immunofluorescence: A431 stained with ARG45813 anti-P Cadherin antibody at 5 μg/ml dilution.
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ARG45813 anti-P Cadherin antibody WB image
Western blot: A431 stained with ARG45813 anti-P Cadherin antibody at 0.5 μg/ml dilution.
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ARG45813 anti-P Cadherin antibody FACS image
Flow Cytometry: A431 stained with ARG45813 anti-P Cadherin antibody at 1 µg/10^6 cells dilution.
