ARG45699
anti-P Cadherin antibody [CH-19]
anti-P Cadherin antibody [CH-19] for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Chicken,Human,Mouse,Rabbit,Rat,Snake
Overview
| Product Description | Mouse Monoclonal antibody [CH-19] recognizes P Cadherin |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Chk, Rb, Snk |
| Tested Application | IHC-P, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | CH-19 |
| Isotype | IgG1 |
| Target Name | P Cadherin |
| Antigen Species | Chicken |
| Immunogen | Synthetic peptide corresponding to C-terminal region of chicken P Cadherin. |
| Conjugation | Un-conjugated |
| Alternate Names | CDH3; cadherin 3, type 1, P-cadherin (placental); PCAD; Cadherin-3; P-cadherin; HJMD; Placental cadherin; CDHP |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Ascites |
| Buffer | Mouse ascites fluid, 1.2% Sodium acetate, 0.01 mg Sodium azide and 2 mg BSA. |
| Preservative | 0.01 mg Sodium azide |
| Stabilizer | 2 mg BSA |
| Concentration | 0.1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | CDH3 |
|---|---|
| Gene Full Name | cadherin 3, type 1, P-cadherin (placental) |
| Background | This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. [provided by RefSeq, Jul 2008] |
| Function | Cadherins are calcium-dependent cell adhesion proteins. [UniProt] |
| Cellular Localization | Cell membrane; ; Membrane. [UniProt] |
| Calculated MW | 59 kDa |
| PTM | Glycoprotein. [UniProt] |
