ARG67282
anti-P2Y12 antibody
anti-P2Y12 antibody for ICC/IF,Immunoprecipitation,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Monoclonal antibody recognizes P2Y12 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IP, WB |
| Host | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG,Kappa |
| Target Name | P2Y12 |
| Conjugation | Un-conjugated |
| Alternate Names | P2RY12; Purinergic Receptor P2Y12; SP1999; P2Y12; HORK3; Purinergic Receptor P2Y, G-Protein Coupled, 12; P2Y12 Platelet ADP Receptor; ADP-Glucose Receptor; P2Y Purinoceptor 12; P2Y(ADP) ; P2Y(Cyc); P2T(AC) ; P2Y(AC) ; ADPG-R; Putative G-Protein Coupled Receptor; G-Protein Coupled Receptor SP1999; Gi-Coupled ADP Receptor HORK3; Purinergic Receptor P2RY12; P2Y(12)R; BDPLT8 |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.05% Proclin 300, 50% glycerol and 0.05% BSA |
| Preservative | 0.05% Proclin 300 |
| Stabilizer | 50% glycerol and 0.05% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | P2RY12 |
| Gene Full Name | Purinergic Receptor P2Y12 |
| Background | The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013] |
| Function | Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation. [UniProt] |
| Calculated MW | 39 kDa |
Images (2) Click the Picture to Zoom In
-
ARG67282 anti-P2Y12 antibody WB image
Western blot: A549 stained with ARG67282 anti-P2Y12 antibody.
-
ARG67282 anti-P2Y12 antibody WB image
Western blot: PC-12 stained with ARG67282 anti-P2Y12 antibody.
