ARG47210
anti-PARP4 antibody
anti-PARP4 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes PARP4 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | PARP4 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human PARP4. |
| Conjugation | Un-conjugated |
| Alternate Names | PARP4; Protein mono-ADP-ribosyltransferase PARP4; ADPRTL1; KIAA0177; PARPL; 193 kDa vault protein; ADP-ribosyltransferase diphtheria toxin-like 4; ARTD4; PARP-related/IalphaI-related H5/proline-rich; PH5P; Poly [ADP-ribose] polymerase 4; PARP-4; Vault poly(ADP-ribose) polymerase; VPARP |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.09% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PARP4 |
| Gene Full Name | poly(ADP-ribose) polymerase family member 4 |
| Background | This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus. [provided by RefSeq, Jul 2008] |
| Function | Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins. [UniProt] |
| Cellular Localization | Cytoplasm; Nucleus; Cytoskeleton. [UniProt] |
| Calculated MW | 193 kDa |
| PTM | Methylation; Phosphoprotein. [UniProt] |
