ARG56193
anti-PAX7 antibody [SPM613]
anti-PAX7 antibody [SPM613] for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody [SPM613] recognizes PAX7 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | SPM613 |
| Isotype | IgG1, kappa |
| Target Name | PAX7 |
| Antigen Species | Human |
| Immunogen | A recombinant PAX7 fragment (aa300-600). |
| Conjugation | Un-conjugated |
| Alternate Names | HUP1; RMS2; PAX7B; Paired box protein Pax-7; HuP1 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Boiling tissue sections in 10mM Tris buffer with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G. |
| Buffer | PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 0.1 mg/ml BSA |
| Concentration | 0.2 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PAX7 |
| Gene Full Name | paired box 7 |
| Background | This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008] |
| Function | Transcription factor playing a role in myogenesis through regulation of muscle precursor cells proliferation. [UniProt] |
| Cellular Localization | Nuclear |
| Calculated MW | 55 kDa |
Images (1) Click the Picture to Zoom In
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ARG56193 anti-PAX7 antibody [SPM613] IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human Rhabdomyosarcoma stained with ARG56193 anti-PAX7 antibody [SPM613].
