ARG10802

anti-PDE4C antibody

anti-PDE4C antibody for Confocal microscopy (Confocal),ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot,Dot blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes PDE4C
Tested Reactivity Hu, Ms, Rat
Tested Application Confocal, Dot, ELISA, ICC/IF, IHC-P, IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name PDE4C
Antigen Species Human
Immunogen Synthetic cyclic peptide around the C-terminus of PDE4C protein. Common to all PDE4C variants.
Conjugation Un-conjugated
Full Name phosphodiesterase 4C, cAMP-specific
Alternate Names cAMP-specific 3',5'-cyclic phosphodiesterase 4C; DPDE1; PDE21; EC 3.1.4.53

Application Instructions

Application Suggestion
Tested Application Dilution
Confocal1:200
Dot1:10000
ELISA1:10000
ICC/IF1:200
IHC-P1:200
IP1:200
WB1:500 - 1:2500
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Calculated MW 80 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 30% Glycerol and 0.5% BSA
Concentration 0.5 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 110385 Mouse PDE4C

GeneID: 5143 Human PDE4C

Swiss-port # Q08493 Human cAMP-specific 3',5'-cyclic phosphodiesterase 4C

Swiss-port # Q3UEI1 Mouse cAMP-specific 3',5'-cyclic phosphodiesterase 4C

Gene Symbol PDE4C
Gene Full Name phosphodiesterase 4C, cAMP-specific
Background The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
Function Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. [UniProt]

Images (1) Click the Picture to Zoom In

  • ARG10802 anti-PDE4C antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human ovarian medulla tissue stained with ARG10802 anti-PDE4C antibody.