ARG10808

anti-PDE7B antibody

anti-PDE7B antibody for Confocal microscopy (Confocal),ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot,Dot blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes PDE7B
Tested Reactivity Hu
Tested Application Confocal, Dot, ELISA, ICC/IF, IHC-P, IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name PDE7B
Species Human
Immunogen Synthetic cyclic peptide common to all PDE7B variants.
Conjugation Un-conjugated
Full Name phosphodiesterase 7B
Alternate Names cAMP-specific 3',5'-cyclic phosphodiesterase 7B; bA472E5.1; EC 3.1.4.53

Application Instructions

Application Suggestion
Tested Application Dilution
Confocal1:200
Dot1:10000
ELISA1:10000
ICC/IF1:200
IHC-P1:200
IP1:250
WB1:500 - 1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Calculated MW 52 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 30% Glycerol and 0.5% BSA
Concentration 0.5 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 27115 Human PDE7B

Swiss-port # Q9NP56 Human cAMP-specific 3',5'-cyclic phosphodiesterase 7B

Gene Symbol PDE7B
Gene Full Name phosphodiesterase 7B
Background The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.[provided by RefSeq, Apr 2009]
Function Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain. [UniProt]

Images (2) Click the Picture to Zoom In

  • ARG10808 anti-PDE7B antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human ovarian medulla tissue stained with ARG10808 anti-PDE7B antibody at 1:150 dilution.

  • ARG10808 anti-PDE7B antibody WB image

    Western blot: Recombinant PDE7B protein stained with ARG10808 anti-PDE7B antibody at 1:1000 dilution.