ARG45630
anti-PDLIM7 antibody
anti-PDLIM7 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PDLIM7 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PDLIM7 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human PDLIM7. |
| Conjugation | Un-conjugated |
| Alternate Names | PDLIM7; PDZ And LIM Domain 7; ENIGMA; PDZ And LIM Domain 7 (Enigma); PDZ And LIM Domain Protein 7; Protein Enigma; LMP; Lim Mineralization Protein 3; LIM Mineralization Protein; LIM Domain Protein; 1110003B01Rik; LMP1; LMP3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 50 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PDLIM7 |
| Gene Full Name | PDZ And LIM Domain 7 |
| Background | The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
| Function | May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway (By similarity). [UniProt] |
| Cellular Localization | Cytoplasm; Cytoskeleton. [UniProt] |
| Calculated MW | 50 kDa |
| PTM | Methylation; Phosphoprotein. [UniProt] |
Images (5) Click the Picture to Zoom In
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ARG45630 anti-PDLIM7 antibody IHC-P image
Immunohistochemistry: Human appendiceal adenocarcinoma stained with ARG45630 anti-PDLIM7 antibody at 2 μg/ml dilution.
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ARG45630 anti-PDLIM7 antibody WB image
Western blot: Hela stained with ARG45630 anti-PDLIM7 antibody at 0.5 μg/ml dilution.
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ARG45630 anti-PDLIM7 antibody FACS image
Flow Cytometry: A431 stained with ARG45630 anti-PDLIM7 antibody at 1 µg/10^6 cells dilution.
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ARG45630 anti-PDLIM7 antibody WB image
Western blot: C6 stained with ARG45630 anti-PDLIM7 antibody at 0.5 μg/ml dilution.
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ARG45630 anti-PDLIM7 antibody WB image
Western blot: RAW264.7 stained with ARG45630 anti-PDLIM7 antibody at 0.5 μg/ml dilution.
