ARG46360
anti-PEAR1 antibody
anti-PEAR1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PEAR1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PEAR1 |
| Antigen Species | Human |
| Immunogen | A 16 amino acid synthetic peptide within the last 50 amino acids of human PEAR1. |
| Conjugation | Un-conjugated |
| Alternate Names | PEAR1; JEDI; MEGF12; Platelet endothelial aggregation receptor 1; Multiple epidermal growth factor-like domains protein 12; hPEAR1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -410°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q5VY43 Human Platelet endothelial aggregation receptor 1 Swiss-port # Q8VIK5 Mouse Platelet endothelial aggregation receptor 1 |
|---|---|
| Gene Symbol | PEAR1 |
| Gene Full Name | platelet endothelial aggregation receptor 1 |
| Background | PEAR1 is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation (Nanda et al., 2005 [PubMed 15851471]).[supplied by OMIM, Mar 2008] |
| Function | Required for SVEP1-mediated platelet activation, via its interaction with SVEP1 and subsequent activation of AKT/mTOR signaling. [UniProt] |
| Cellular Localization | Cell membrane ; Cell projection. [UniProt] |
| Calculated MW | 111 kDa |
| PTM | Phosphoprotein; Disulfide bond; Glycoprotein. [UniProt] |
