anti-PFKP antibody

anti-PFKP antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Cancer antibody; Metabolism antibody; Signaling Transduction antibody


Product Description Rabbit Polyclonal antibody recognizes PFKP
Tested Reactivity Hu
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name PFKP
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 754-784 (C-terminus) of Human PFKP.
Conjugation Un-conjugated
Alternate Names Phosphohexokinase; PFK-C; EC; 6-phosphofructokinase type C; Phosphofructo-1-kinase isozyme C; ATP-PFK; ATP-dependent 6-phosphofructokinase, platelet type; PFK-P; PFKF

Application Instructions

Application Suggestion
Tested Application Dilution
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control T47D


Form Liquid
Purification Purification with Protein G.
Buffer PBS and 0.09% (W/V) Sodium azide
Preservative 0.09% (W/V) Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 5214 Human PFKP

Swiss-port # Q01813 Human ATP-dependent 6-phosphofructokinase, platelet type

Gene Symbol PFKP
Gene Full Name phosphofructokinase, platelet
Background The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.[supplied by OMIM, Mar 2008]
Function Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. [UniProt]
Cellular Localization Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03184}.
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Research Area Cancer antibody; Metabolism antibody; Signaling Transduction antibody
Calculated MW 86 kDa
PTM GlcNAcylation decreases enzyme activity.

Images (2) Click the Picture to Zoom In

  • ARG54874 anti-PFKP antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human breast carcinoma tissue stained with ARG54874 anti-PFKP antibody.

  • ARG54874 anti-PFKP antibody WB image

    Western blot: 35 µg of T47D cell lysate stained with ARG54874 anti-PFKP antibody.