ARG46372
anti-PIAS2 antibody
anti-PIAS2 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PIAS2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PIAS2 |
| Antigen Species | Human |
| Immunogen | A 18 amino acid synthetic peptide within the last 50 amino acids of human PIAS2. |
| Conjugation | Un-conjugated |
| Alternate Names | PIAS2; Miz1; Protein inhibitor of activated STAT x; Protein inhibitor of activated STAT2; MIZ1; EC 6.3.2.-; PIASX-ALPHA; SIZ2; PIASX-BETA; ARIP3; DAB2-interacting protein; E3 SUMO-protein ligase PIAS2; MIZ; Androgen receptor-interacting protein 3; PIAS-NY protein; PIASX; DIP; Msx-interacting zinc finger protein; ZMIZ4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PIAS2 |
| Gene Full Name | protein inhibitor of activated STAT, 2 |
| Background | This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. [provided by RefSeq, Aug 2011] |
| Calculated MW | 68 kDa |
| PTM | Sumoylated. |
Images (2) Click the Picture to Zoom In
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ARG46372 anti-PIAS2 antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG46372 anti-PIAS2 antibody.
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ARG46372 anti-PIAS2 antibody WB image
Western blot: Rat brain stained with ARG46372 anti-PIAS2 antibody.
