ARG46376
anti-PIEZO2 antibody
anti-PIEZO2 antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PIEZO2 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PIEZO2 |
| Antigen Species | Human |
| Immunogen | A 19 amino acid synthetic peptide within the last 50 amino acids of human PIEZO2. |
| Conjugation | Un-conjugated |
| Alternate Names | PIEZO2; piezo-type mechanosensitive ion channel component 2; C18orf30; C18orf58; DA3; DA5; DAIPT; FAM38B; FAM38B2; HsT748; HsT771; MWKS |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Observed Size | 235 kDa |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8CD54 Mouse Piezo-type mechanosensitive ion channel component 2 Swiss-port # Q9H5I5 Human Piezo-type mechanosensitive ion channel component 2 |
|---|---|
| Gene Symbol | PIEZO2 |
| Gene Full Name | piezo-type mechanosensitive ion channel component 2 |
| Background | e protein encoded by this gene contains more than thirty transmembrane domains and likely functions as part of mechanically-activated (MA) cation channels. These channels serve to connect mechanical forces to biological signals. The encoded protein quickly adapts MA currents in somatosensory neurons. Defects in this gene are a cause of type 5 distal arthrogryposis. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014] |
| Function | Pore-forming subunit of the mechanosensitive non-specific cation Piezo channel required for rapidly adapting mechanically activated (MA) currents and has a key role in sensing touch and tactile pain |
| Cellular Localization | Cell membrane. [UniProt] |
| Calculated MW | 233,305 kDa |
Images (2) Click the Picture to Zoom In
-
ARG46376 anti-PIEZO2 antibody WB image
Western blot: SK-N-SH stained with ARG46376 anti-PIEZO2 antibody.
-
ARG46376 anti-PIEZO2 antibody WB image
Western blot: Mouse skeletal muscle stained with ARG46376 anti-PIEZO2 antibody.
