ARG45591
anti-PMM2 antibody
anti-PMM2 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PMM2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PMM2 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human PMM2. |
| Conjugation | Un-conjugated |
| Alternate Names | PMM2; Phosphomannomutase 2; CDG1a; CDGS; PMI1; PMI; Mannose-6-Phosphate Isomerase; Phosphomannose Isomerase 1; EC 5.4.2.8; PMM 2; CDG1; Congenital Disorder Of Glycosylation, Type Ia |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 28 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PMM2 |
| Gene Full Name | Phosphomannomutase 2 |
| Background | The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I. [provided by RefSeq, Jul 2008] |
| Function | Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. [UniProt] |
| Cellular Localization | Cytoplasm; Nucleus. [UniProt] |
| Calculated MW | 28 kDa |
| PTM | Acetylation. [UniProt] |
Images (5) Click the Picture to Zoom In
-
ARG45591 anti-PMM2 antibody ICC/IF image
Immunofluorescence: Hela stained with ARG45591 anti-PMM2 antibody at 5 μg/ml dilution.
-
ARG45591 anti-PMM2 antibody WB image
Western blot: HepG2 and A549 stained with ARG45591 anti-PMM2 antibody at 0.5 μg/ml dilution.
-
ARG45591 anti-PMM2 antibody FACS image
Flow Cytometry: HEL stained with ARG45591 anti-PMM2 antibody at 1 µg/10^6 cells dilution.
-
ARG45591 anti-PMM2 antibody WB image
Western blot: Rat small intestines stained with ARG45591 anti-PMM2 antibody at 0.5 μg/ml dilution.
-
ARG45591 anti-PMM2 antibody WB image
Western blot: Mouse small intestines stained with ARG45591 anti-PMM2 antibody at 0.5 μg/ml dilution.
