ARG45464
anti-POC1A antibody
anti-POC1A antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes POC1A |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | POC1A |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human POC1A. |
| Conjugation | Un-conjugated |
| Alternate Names | POC1A; POC1 Centriolar Protein A; WDR51A; POC1 Centriolar Protein Homolog A; WD Repeat-Containing Protein 51A; Proteome Of Centriole Protein 1A; WD Repeat Domain 51A; DKFZP434C245; POC1 Centriolar Protein Homolog A (Chlamydomonas); PIX2; SOFT; Pix2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 40 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | POC1A |
| Gene Full Name | POC1 Centriolar Protein A |
| Background | POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutations in this gene result in short stature, onychodysplasia, facial dysmorphism, and hypotrichosis (SOFT) syndrome. [provided by RefSeq, Sep 2012] |
| Function | Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Acts in concert with POC1B to ensure centriole integrity and proper mitotic spindle formation. [UniProt] |
| Cellular Localization | Cell projection; Cytoplasm; Cytoskeleton. [UniProt] |
| Calculated MW | 45 kDa |
Images (8) Click the Picture to Zoom In
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ARG45464 anti-POC1A antibody IHC-P image
Immunohistochemistry: Human prostate cancer stained with ARG45464 anti-POC1A antibody at 2 μg/ml dilution.
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ARG45464 anti-POC1A antibody ICC/IF image
Immunofluorescence: A549 stained with ARG45464 anti-POC1A antibody at 5 μg/ml dilution.
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ARG45464 anti-POC1A antibody WB image
Western blot: PC-3 stained with ARG45464 anti-POC1A antibody at 0.5 μg/ml dilution.
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ARG45464 anti-POC1A antibody FACS image
Flow Cytometry: PC-3 stained with ARG45464 anti-POC1A antibody at 1 µg/10^6 cells dilution.
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ARG45464 anti-POC1A antibody IHC-P image
Immunohistochemistry: Rat testis stained with ARG45464 anti-POC1A antibody at 2 μg/ml dilution.
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ARG45464 anti-POC1A antibody WB image
Western blot: Rat testis stained with ARG45464 anti-POC1A antibody at 0.5 μg/ml dilution.
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ARG45464 anti-POC1A antibody IHC-P image
Immunohistochemistry: Mouse testis stained with ARG45464 anti-POC1A antibody at 2 μg/ml dilution.
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ARG45464 anti-POC1A antibody WB image
Western blot: Mouse testis stained with ARG45464 anti-POC1A antibody at 0.5 μg/ml dilution.
