ARG47236
anti-POLR2J antibody
anti-POLR2J antibody for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes POLR2J |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | POLR2J |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human POLR2J. |
| Conjugation | Un-conjugated |
| Alternate Names | POLR2J; DNA-directed RNA polymerase II subunit RPB11-a; POLR2J1; DNA-directed RNA polymerase II subunit J-1; RNA polymerase II 13.3 kDa subunit |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.09% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P52435 Human DNA-directed RNA polymerase II subunit RPB11-a |
|---|---|
| Gene Symbol | POLR2J |
| Gene Full Name | RNA polymerase II subunit J |
| Background | This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene exists as a heterodimer with another polymerase subunit; together they form a core subassembly unit of the polymerase. Two similar genes are located nearby on chromosome 7q22.1 and a pseudogene is found on chromosome 7p13. [provided by RefSeq, Jul 2008] |
| Function | Core component of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase which synthesizes mRNA precursors and many functional non-coding RNAs using the four ribonucleoside triphosphates as substrates. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 13 kDa |
| PTM | Acetylation. [UniProt] |
