ARG47242
anti-PPP5C antibody
anti-PPP5C antibody for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes PPP5C |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Target Name | PPP5C |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human PPP5C. |
| Conjugation | Un-conjugated |
| Alternate Names | PPP5C; Serine/threonine-protein phosphatase 5; PPP5; Protein phosphatase T; PP-T; PPT |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS, 0.09% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P53041 Human Serine/threonine-protein phosphatase 5 |
|---|---|
| Gene Symbol | PPP5C |
| Gene Full Name | protein phosphatase 5 catalytic subunit |
| Background | This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011] |
| Function | Serine/threonine-protein phosphatase that dephosphorylates a myriad of proteins involved in different signaling pathways including the kinases CSNK1E, ASK1/MAP3K5, PRKDC and RAF1, the nuclear receptors NR3C1, PPARG, ESR1 and ESR2, SMAD proteins and TAU/MAPT. [UniProt] |
| Cellular Localization | Nucleus; Cytoplasm; Cell membrane; Membrane. [UniProt] |
| Calculated MW | 57 kDa |
| PTM | Acetylation. [UniProt] |
