ARG45776
anti-PRMT8 antibody
anti-PRMT8 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PRMT8 |
|---|---|
| Tested Reactivity | Hu, Rat |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PRMT8 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human PRMT8. |
| Conjugation | Un-conjugated |
| Alternate Names | PRMT8; Protein Arginine Methyltransferase 8; HRMT1L3; HRMT1L4; Heterogeneous Nuclear Ribonucleoprotein Methyltransferase-Like Protein 4; Protein Arginine N-Methyltransferase 8; HMT1 HnRNP Methyltransferase-Like 3 (S. Cerevisiae); HMT1 HnRNP Methyltransferase-Like 4 (S. Cerevisiae); Protein Arginine N-Methyltransferase 4; HMT1 HnRNP Methyltransferase-Like 3; Arginine Methyltransferase 8; EC 2.1.1.319; EC 2.1.1.77 47; EC 2.1.1 47 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 45 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.01% Sodium azide and 4% Trehalose. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9NR22 Human Protein arginine N-methyltransferase 8 |
|---|---|
| Gene Symbol | PRMT8 |
| Gene Full Name | Protein Arginine Methyltransferase 8 |
| Background | Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein compartmentalization, and possibly protein translation (Lee et al., 2005 [PubMed 16051612]).[supplied by OMIM, Mar 2008] |
| Function | S-adenosyl-L-methionine-dependent and membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA) in proteins such as NIFK, myelin basic protein, histone H4, H2A and H2A/H2B dimer. [UniProt] |
| Cellular Localization | Cell membrane; Membrane. [UniProt] |
| Calculated MW | 45 kDa |
| PTM | Lipoprotein; Methylation; Myristate. [UniProt] |
Images (5) Click the Picture to Zoom In
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ARG45776 anti-PRMT8 antibody IHC-P image
Immunohistochemistry: Human breast cancer stained with ARG45776 anti-PRMT8 antibody at 2 μg/ml dilution.
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ARG45776 anti-PRMT8 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG45776 anti-PRMT8 antibody at 2 μg/ml dilution.
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ARG45776 anti-PRMT8 antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG45776 anti-PRMT8 antibody at 2 μg/ml dilution.
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ARG45776 anti-PRMT8 antibody WB image
Western blot: Rat brain stained with ARG45776 anti-PRMT8 antibody at 0.5 μg/ml dilution.
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ARG45776 anti-PRMT8 antibody WB image
Western blot: Mouse brain stained with ARG45776 anti-PRMT8 antibody at 0.5 μg/ml dilution.
