ARG67380
anti-PRSS1 antibody [SQab30422]
anti-PRSS1 antibody [SQab30422] for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Rabbit Monoclonal antibody [SQab30422] recognizes PRSS1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | SQab30422 |
| Isotype | IgG |
| Target Name | PRSS1 |
| Immunogen | Synthetic peptide |
| Conjugation | Un-conjugated |
| Alternate Names | PRSS1; TRP1; Serine Protease 1; Digestive Zymogen; TRY1; Anionic Trypsin-I; Cationic Trypsinogen; Protease Serine 1; Nonfunctional Trypsin 1; TCR V Beta 4.1; Protease, Serine 1; Trypsinogen A; Anionic Trypsin I; Trypsinogen 1; Pretrypsinogen I; Trypsin 1; Beta-Trypsin; Trypsin-1; Trypsin I; Trypsin; TRYP1; TRY4 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 40% Glycerol and 0.05% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PRSS1 |
| Gene Full Name | Serine Protease 1 |
| Background | This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. [provided by RefSeq, Jul 2008] |
| Function | Has activity against the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg-Mec. The single-chain form is more active than the two-chain form against all of these substrates |
| Cellular Localization | Secreted |
| Calculated MW | 26.5 kDa |
| PTM | #Disulfide bond #Sulfation #Zymogen |
Images (1) Click the Picture to Zoom In
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ARG67380 anti-PRSS1 antibody [SQab30422] IHC-P image
Immunohistochemistry: Human pancreas stained with ARG67380 anti-PRSS1 antibody [SQab30422].
