ARG45553
anti-PRUNE antibody
anti-PRUNE antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PRUNE |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PRUNE |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human PRUNE. |
| Conjugation | Un-conjugated |
| Alternate Names | PRUNE1; Prune Exopolyphosphatase 1; DRES-17; H-PRUNE; HTCD37; PRUNE; Drosophila-Related Expressed Sequence 17; Exopolyphosphatase PRUNE1; Protein Prune Homolog 1; DRES17; Prune Homolog (Drosophila); EC 3.6.1.1; NMIHBA; HTcD37; Hprune |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 60 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PRUNE1 |
| Gene Full Name | Prune Exopolyphosphatase 1 |
| Background | This gene encodes a member of the DHH protein superfamily of phosphoesterases. This protein has been found to function as both a nucleotide phosphodiesterase and an exopolyphosphatase. This protein is believed to stimulate cancer progression and metastases through the induction of cell motility. A pseuodgene has been identified on chromosome 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
| Function | Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, migration and differentiation, and acts as a negative regulator of NME1. Plays a role in the regulation of neurogenesis. [UniProt] |
| Cellular Localization | Cell junction; Cytoplasm; Nucleus. [UniProt] |
| Calculated MW | 50 kDa |
| PTM | Acetylation; Phosphoprotein. [UniProt] |
Images (5) Click the Picture to Zoom In
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ARG45553 anti-PRUNE antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG45553 anti-PRUNE antibody at 5 μg/ml dilution.
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ARG45553 anti-PRUNE antibody WB image
Western blot: MCF-7 stained with ARG45553 anti-PRUNE antibody at 0.5 μg/ml dilution.
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ARG45553 anti-PRUNE antibody FACS image
Flow Cytometry: 293T stained with ARG45553 anti-PRUNE antibody at 1 µg/10^6 cells dilution.
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ARG45553 anti-PRUNE antibody WB image
Western blot: Rat brain stained with ARG45553 anti-PRUNE antibody at 0.5 μg/ml dilution.
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ARG45553 anti-PRUNE antibody WB image
Western blot: Mouse brain stained with ARG45553 anti-PRUNE antibody at 0.5 μg/ml dilution.
