ARG66345

anti-PSA antibody [SQab1895]

anti-PSA antibody [SQab1895] for IHC-Formalin-fixed paraffin-embedded sections and Human

Overview

Product Description Recombinant Rabbit Monoclonal antibody [SQab1895] recognizes PSA
Tested Reactivity Hu
Tested Application IHC-P
Host Rabbit
Clonality Monoclonal
Clone SQab1895
Isotype IgG
Target Name PSA
Antigen Species Human
Immunogen Synthetic peptide within aa. 150-250 of Human PSA.
Conjugation Un-conjugated
Full Name kallikrein-related peptidase 3
Alternate Names Prostate-specific antigen; Gamma-seminoprotein; APS; PSA; EC 3.4.21.77; Kallikrein-3; P-30 antigen; Semenogelase; hK3; Seminin; KLK2A1

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:100 - 1:200
Application Note IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0), primary antibody incubate at RT for 30 min.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Calculated MW 29 kDa

Properties

Form Liquid
Purification Purification with Protein A.
Buffer PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
Preservative 0.01% Sodium azide
Stabilizer 40% Glycerol and 0.05% BSA
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 354 Human KLK3

Swiss-port # P07288 Human Prostate-specific antigen

Gene Symbol KLK3
Gene Full Name kallikrein-related peptidase 3
Background Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Function Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum. [UniProt]
Highlight Related products:
PSA antibodies; PSA ELISA Kits; PSA Duos / Panels; Anti-Rabbit IgG secondary antibodies;
Related news:
Cancer Pathology Markers (SQ clones)

Images (1) Click the Picture to Zoom In

  • ARG66345 anti-PSA antibody [SQab1895] IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded prostate cancer tissue stained with ARG66345 anti-PSA antibody [SQab1895]. Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0).