ARG46413

anti-PTK7 / CCK4 antibody

anti-PTK7 / CCK4 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes PTK7 / CCK4
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name PTK7 / CCK4
Antigen Species Human
Immunogen A 18 amino acid synthetic peptide within the last 50 amino acids of human PTK7 / CCK4.
Conjugation Un-conjugated
Alternate Names PTK7; PTK7; Protein Tyrosine Kinase 7 (Inactive); CCK4; Colon Carcinoma Kinase 4; Inactive Tyrosine-Protein Kinase 7; Pseudo Tyrosine Kinase Receptor 7; PTK7 Protein Tyrosine Kinase 7; Tyrosine-Protein Kinase-Like 7; CCK-4; Protein Tyrosine Kinase 7; Protein-Tyrosine Kinase 7

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-PAssay-dependent
WBAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Purification Affinity chromatography purified
Buffer PBS and 0.02% Sodium azide.
Preservative 0.02% Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 5754 Human PTK7

GeneID: 71461 Mouse PTK7

Swiss-port # Q13308 Human Inactive tyrosine-protein kinase 7

Swiss-port # Q8BKG3 Mouse Inactive tyrosine-protein kinase 7

Gene Symbol PTK7
Gene Full Name Protein Tyrosine Kinase 7 (Inactive)
Background This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Function Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis. [Uniprot]
Cellular Localization Cell junction, Membrane. [Uniprot]
PTM Disulfide bond, Glycoprotein, Phosphoprotein. [Uniprot]

Images (3) Click the Picture to Zoom In

  • ARG46413 anti-PTK7 / CCK4 antibody IHC-P image

    Immunohistochemistry: Human colon stained with ARG46413 anti-PTK7 / CCK4 antibody.

  • ARG46413 anti-PTK7 / CCK4 antibody ICC/IF image

    Immunofluorescence: Human Colon stained with ARG46413 anti-PTK7 / CCK4 antibody.

  • ARG46413 anti-PTK7 / CCK4 antibody WB image

    Western blot: Human colon stained with ARG46413 anti-PTK7 / CCK4 antibody.