ARG47250
anti-PTP zeta / Phosphacan antibody
anti-PTP zeta / Phosphacan antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes PTP zeta / Phosphacan |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | PTP zeta / Phosphacan |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human PTP zeta / Phosphacan. |
| Conjugation | Un-conjugated |
| Alternate Names | PTPRZ1; Receptor-type tyrosine-protein phosphatase zeta; HTPZP2; PTPRZ; PTPRZ2; PTPZ; Protein-tyrosine phosphatase receptor type Z polypeptide 1; Protein-tyrosine phosphatase receptor type Z polypeptide 2; R-PTP-zeta-2 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.09% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P23471 Human Receptor-type tyrosine-protein phosphatase zeta |
|---|---|
| Gene Symbol | PTPRZ1 |
| Gene Full Name | protein tyrosine phosphatase receptor type Z1 |
| Background | This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011] |
| Function | Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades (By similarity). [UniProt] |
| Cellular Localization | Cell membrane; Membrane; Secreted. [UniProt] |
| Calculated MW | 255 kDa |
| PTM | Disulfide bond; Glycoprotein; Phosphoprotein; Proteoglycan. [UniProt] |
