ARG45415
anti-PTRF antibody
anti-PTRF antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PTRF |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PTRF |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human PTRF. |
| Conjugation | Un-conjugated |
| Alternate Names | CAVIN1; Caveolae Associated Protein 1; Cavin-1; Polymerase I And Transcript Release Factor; CGL4; PTRF; Congenital Generalized Lipodystrophy 4; Caveolae-Associated Protein 1; RNA Polymerase I And Transcript Release Factor; TTF-I Interacting Peptide 12; FKSG13; CAVIN |
Application Instructions
| Application Suggestion |
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 50-55 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O54724 Mouse Polymerase I and transcript release factor Swiss-port # Q6NZI2 Human Polymerase I and transcript release factor |
|---|---|
| Gene Symbol | CAVIN1 |
| Gene Full Name | Caveolae Associated Protein 1 |
| Background | This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy. [provided by RefSeq, Nov 2009] |
| Function | Plays an important role in caveolae formation and organization. Essential for the formation of caveolae in all tissues. [UniProt] |
| Cellular Localization | Cell membrane; Cytoplasm; Endoplasmic reticulum; Membrane; Microsome. [UniProt] |
| Calculated MW | 43 kDa |
| PTM | Acetylation; Isopeptide bond; Phosphoprotein; Ubl conjugation. [UniProt] |
Images (8) Click the Picture to Zoom In
-
ARG45415 anti-PTRF antibody IHC-P image
Immunohistochemistry: Human glioblastoma stained with ARG45415 anti-PTRF antibody at 2 μg/ml dilution.
-
ARG45415 anti-PTRF antibody ICC/IF image
Immunofluorescence: Hela stained with ARG45415 anti-PTRF antibody at 5 μg/ml dilution.
-
ARG45415 anti-PTRF antibody WB image
Western blot: Hela stained with ARG45415 anti-PTRF antibody at 0.25 μg/ml dilution.
-
ARG45415 anti-PTRF antibody FACS image
Flow Cytometry: SiHa stained with ARG45415 anti-PTRF antibody at 1 µg/10^6 cells dilution.
-
ARG45415 anti-PTRF antibody IHC-P image
Immunohistochemistry: Rat lung stained with ARG45415 anti-PTRF antibody at 2 μg/ml dilution.
-
ARG45415 anti-PTRF antibody WB image
Western blot: Rat heart stained with ARG45415 anti-PTRF antibody at 0.25 μg/ml dilution.
-
ARG45415 anti-PTRF antibody IHC-P image
Immunohistochemistry: Mouse lung stained with ARG45415 anti-PTRF antibody at 2 μg/ml dilution.
-
ARG45415 anti-PTRF antibody WB image
Western blot: Mouse heart stained with ARG45415 anti-PTRF antibody at 0.25 μg/ml dilution.
