ARG45525
anti-Pannexin 1 antibody
anti-Pannexin 1 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Pannexin 1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Pannexin 1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human Pannexin 1. |
| Conjugation | Un-conjugated |
| Alternate Names | PANX1; Pannexin 1; MRS1; UNQ2529; PX1; Pannexin-1; Innexin; OZEMA7; OOMD7 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 48 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PANX1 |
| Gene Full Name | Pannexin 1 |
| Background | The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties. [provided by RefSeq, Jul 2008] |
| Function | Ion channel involved in a variety of physiological functions such as blood pressure regulation, apoptotic cell clearance and oogenesis . [UniProt] |
| Cellular Localization | Cell membrane; Endoplasmic reticulum; Membrane. [UniProt] |
| Calculated MW | 48 kDa |
| PTM | Disulfide bond; Glycoprotein; Phosphoprotein; S-nitrosylation. [UniProt] |
Images (5) Click the Picture to Zoom In
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ARG45525 anti-Pannexin 1 antibody ICC/IF image
Immunofluorescence: MCF-7 stained with ARG45525 anti-Pannexin 1 antibody at 5 μg/ml dilution.
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ARG45525 anti-Pannexin 1 antibody WB image
Western blot: Hela stained with ARG45525 anti-Pannexin 1 antibody at 0.5 μg/ml dilution.
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ARG45525 anti-Pannexin 1 antibody FACS image
Flow Cytometry: MCF-7 stained with ARG45525 anti-Pannexin 1 antibody at 1 µg/10^6 cells dilution.
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ARG45525 anti-Pannexin 1 antibody WB image
Western blot: Rat brain stained with ARG45525 anti-Pannexin 1 antibody at 0.5 μg/ml dilution.
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ARG45525 anti-Pannexin 1 antibody WB image
Western blot: Mouse brain stained with ARG45525 anti-Pannexin 1 antibody at 0.5 μg/ml dilution.
