ARG45223
anti-RGS12 antibody
anti-RGS12 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes RGS12 |
|---|---|
| Tested Reactivity | Hu, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | RGS12 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human RGS12. |
| Conjugation | Un-conjugated |
| Alternate Names | RGS12; Regulator Of G Protein Signaling 12; Regulator Of G-Protein Signaling 12; Regulator Of G-Protein Signalling 12 |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 156 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O08774 Rat Regulator of G-protein signaling 12 Swiss-port # O14924 Human Regulator of G-protein signaling 12 |
|---|---|
| Gene Symbol | RGS12 |
| Gene Full Name | Regulator Of G Protein Signaling 12 |
| Background | This gene encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor. This protein may play a role in tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008] |
| Function | Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form.. [UniProt] |
| Cellular Localization | Cell projection; Cytoplasm; Nucleus; Synapse. [UniProt] |
| Calculated MW | 156 kDa |
| PTM | Isopeptide bond; Methylation; Phosphoprotein; Ubl conjugation. [UniProt] |
Images (4) Click the Picture to Zoom In
-
ARG45223 anti-RGS12 antibody IHC-P image
Immunohistochemistry: Human rectum adenocarcinoma stained with ARG45223 anti-RGS12 antibody at 2 μg/ml dilution.
-
ARG45223 anti-RGS12 antibody ICC/IF image
Immunofluorescence: A549 stained with ARG45223 anti-RGS12 antibody at 5 ug/ml dilution.
-
ARG45223 anti-RGS12 antibody WB image
Western blot: RT4, SH-SY5Y, and HepG2 stained with ARG45223 anti-RGS12 antibody at 0.5 μg/ml dilution.
-
ARG45223 anti-RGS12 antibody IHC-P image
Immunohistochemistry: Rat brian stained with ARG45223 anti-RGS12 antibody at 2 μg/ml dilution.
