ARG46438
anti-RIMS2 antibody
anti-RIMS2 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes RIMS2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | RIMS2 |
| Antigen Species | Human |
| Immunogen | A 17 amino acid synthetic peptide within the last 50 amino acids of human RIMS2. |
| Conjugation | Un-conjugated |
| Alternate Names | RIMS2; regulating synaptic membrane exocytosis 2; Rim2; OBOE; RIM2; RAB3IP3; KIAA0751; Regulating synaptic membrane exocytosis protein 2; Rab-3-interacting molecule 2; RIM 2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 128 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -488°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | RIMS2 |
| Gene Full Name | regulating synaptic membrane exocytosis 2 |
| Background | The protein encoded by this gene is a presynaptic protein that interacts with RAB3, a protein important for normal neurotransmitter release. The encoded protein can also bind several other synaptic proteins, including UNC-13 homolog B, ELKS/Rab6-interacting/CAST family member 1, and synaptotagmin 1. This protein is involved in synaptic membrane exocytosis. Polymorphisms in this gene have been associated with degenerative lumbar scoliosis. [provided by RefSeq, Feb 2017] |
| Function | Rab effector involved in exocytosis. May act as scaffold protein. Plays a role in dendrite formation by melanocytes (PubMed:23999003). [UniProt] |
| Cellular Localization | Cell membrane. [UniProt] |
| Calculated MW | 39, 128, 148, 170 kDa |
| PTM | Phosphoprotein. [UniProt] |
