ARG44920
anti-RNF146 antibody
anti-RNF146 antibody for Immunoprecipitation,Western blot and Human,Rat
Overview
| Product Description | Mouse Monoclonal antibody recognizes RNF146 |
|---|---|
| Tested Reactivity | Hu, Rat |
| Tested Application | IP, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Target Name | RNF146 |
| Antigen Species | Human |
| Epitope | NLARESSADG ADSVSAQSGA SVQPLVSSVR PLTSVDGQLT SPATPSPDAS TSLEDSFAHL QLSGDNTAER SHRGEGEEDH ESPSSGRVPA PDTSIEETES DASSDSEDVS AVVAQHSLTQ QRLLVSNANQ |
| Conjugation | Un-conjugated |
| Alternate Names | RNF146; Ring Finger Protein 146; Dactylidin; RING-Type E3 Ubiquitin Transferase RNF146; E3 Ubiquitin-Protein Ligase RNF146; DKFZp434O1427; DJ351K20.1; Iduna; RING Finger Protein 146; EC 2.3.2.27 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q5XIK5 Rat E3 ubiquitin-protein ligase RNF146 Swiss-port # Q9NTX7 Human E3 ubiquitin-protein ligase RNF146 |
|---|---|
| Gene Symbol | RNF146 |
| Gene Full Name | Ring Finger Protein 146 |
| Background | Enables poly-ADP-D-ribose binding activity and ubiquitin-protein transferase activity. Involved in positive regulation of canonical Wnt signaling pathway; protein ubiquitination; and ubiquitin-dependent protein catabolic process. Located in cytosol; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | Promotes cell survival after gamma-irradiation. Facilitates DNA repair. [UniProt] |
| Cellular Localization | Cytoplasm, Nucleus. [UniProt] |
| Calculated MW | 39 kDa |
| PTM | Isopeptide bond, Phosphoprotein, Ubl conjugation. [UniProt] |
Images (2) Click the Picture to Zoom In
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ARG44920 anti-RNF146 antibody WB image
Western blot: Rat brain stained with ARG44920 anti-RNF146 antibody at 1 µg/mL dilution.
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ARG44920 anti-RNF146 antibody IP image
Immunoprecipitation: Rat brain lysate immunoprecipitated with 2.5 µg of ARG44920 anti-RNF146 antibody.
