anti-Retinoid X Receptor beta antibody [147]

anti-Retinoid X Receptor beta antibody [147] for Western blot and Mouse,Rat

Cancer antibody; Gene Regulation antibody; Signaling Transduction antibody


Product Description Mouse Monoclonal antibody [147] recognizes Retinoid X Receptor beta
Tested Reactivity Ms, Rat
Tested Application WB
Host Mouse
Clonality Monoclonal
Clone 147
Isotype IgG1
Target Name Retinoid X Receptor beta
Antigen Species Mouse
Immunogen Synthetic peptide corresponding to amino acid residues from the hinge region conjugated to KLH
Conjugation Un-conjugated
Alternate Names Retinoic acid receptor RXR-beta; DAUDI6; Retinoid X receptor beta; H-2RIIBP; NR2B2; RCoR-1; Nuclear receptor subfamily 2 group B member 2

Application Instructions

Application Suggestion
Tested Application Dilution
Application Note Specific for the ~48k RXR-β protein.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Protein G purified
Buffer 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol
Stabilizer 0.1 mg/ml BSA, 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 20182 Mouse RXRB

Swiss-port # P28704 Mouse Retinoic acid receptor RXR-beta

Gene Symbol Rxrb
Gene Full Name retinoid X receptor beta
Background Retinoic acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXRα, β and γ), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).
Function Nuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis retinoic acid (9C-RA). Binds to both, class I regulatory element of major histocompatibility class I genes (CRE) and the estrogen response element (ERE). [UniProt]
Research Area Cancer antibody; Gene Regulation antibody; Signaling Transduction antibody
Calculated MW 57 kDa

Images (1) Click the Picture to Zoom In

  • ARG52415 anti-Retinoid X Receptor beta antibody [147] WB image

    Western blot: Hippocampal lysate showing specific immunolabeling of the ~48 kDa Retinoid X Receptor beta protein stained with ARG52415 anti-Retinoid X Receptor beta antibody [147]