ARG45825
anti-SAMSN1 antibody
anti-SAMSN1 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SAMSN1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SAMSN1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human SAMSN1. |
| Conjugation | Un-conjugated |
| Alternate Names | SAMSN1; SAM Domain, SH3 Domain And Nuclear Localization Signals 1 ; Hematopoietic adaptor containing SH3 and SAM domains 1; SH3-SAM adaptor protein; SLy2; Nash1; SH3D6B; SAM domain, SH3 domain and nuclear localization signals protein 1; NASH1; SAM domain-containing protein SAMSN-1; HACS1; SASH2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 50 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P57725 Mouse SAM domain-containing protein SAMSN-1 Swiss-port # Q9NSI8 Human SAM domain-containing protein SAMSN-1 |
|---|---|
| Gene Symbol | SAMSN1 |
| Gene Full Name | SAM Domain, SH3 Domain And Nuclear Localization Signals 1 |
| Background | SAMSN1 is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains (Claudio et al., 2001 [PubMed 11536050]).[supplied by OMIM, Mar 2008] |
| Function | Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation (By similarity). [UniProt] |
| Cellular Localization | Cell projection; Cytoplasm; Nucleus. [UniProt] |
| Calculated MW | 42 kDa |
| PTM | Phosphoprotein. [UniProt] |
Images (6) Click the Picture to Zoom In
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ARG45825 anti-SAMSN1 antibody IHC-P image
Immunohistochemistry: Human tonsil stained with ARG45825 anti-SAMSN1 antibody at 2 μg/ml dilution.
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ARG45825 anti-SAMSN1 antibody ICC/IF image
Immunofluorescence: HEL stained with ARG45825 anti-SAMSN1 antibody at 5 μg/ml dilution.
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ARG45825 anti-SAMSN1 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG45825 anti-SAMSN1 antibody at 2 μg/ml dilution.
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ARG45825 anti-SAMSN1 antibody WB image
Western blot: K562 stained with ARG45825 anti-SAMSN1 antibody at 0.5 μg/ml dilution.
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ARG45825 anti-SAMSN1 antibody FACS image
Flow Cytometry: K562 stained with ARG45825 anti-SAMSN1 antibody at 1 µg/10^6 cells dilution.
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ARG45825 anti-SAMSN1 antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG45825 anti-SAMSN1 antibody at 2 μg/ml dilution.
