ARG45783
anti-SARI antibody
anti-SARI antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SARI |
|---|---|
| Tested Reactivity | Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SARI |
| Antigen Species | Mouse |
| Immunogen | Recombinant protein containing to mouse SARI. |
| Conjugation | Un-conjugated |
| Alternate Names | BATF2; Basic Leucine Zipper ATF-Like Transcription Factor 2; SARI; Basic Leucine Zipper Transcriptional Factor ATF-Like 2; Basic Leucine Zipper Transcription Factor, ATF-Like 2; Suppressor Of AP-1 Regulated By IFN; MGC20410; B-ATF-2; Suppressor Of AP-1, Regulated By IFN |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 25 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | BATF2 |
|---|---|
| Gene Full Name | Basic Leucine Zipper ATF-Like Transcription Factor 2 |
| Background | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in defense response to protozoan; myeloid dendritic cell differentiation; and regulation of transcription by RNA polymerase II. Part of RNA polymerase II transcription regulator complex. [provided by Alliance of Genome Resources, Feb 2025] |
| Function | AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes (By similarity). Selectively suppresses CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CCN1 and inhibits CCN1-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CCN1 promoter. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 30 kDa |
Images (4) Click the Picture to Zoom In
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ARG45783 anti-SARI antibody IHC-P image
Immunohistochemistry: Mouse kidney stained with ARG45783 anti-SARI antibody at 2 μg/ml dilution.
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ARG45783 anti-SARI antibody WB image
Western blot: C6 stained with ARG45783 anti-SARI antibody at 0.5 μg/ml dilution.
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ARG45783 anti-SARI antibody IHC-P image
Immunohistochemistry: Rat kidney stained with ARG45783 anti-SARI antibody at 2 μg/ml dilution.
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ARG45783 anti-SARI antibody WB image
Western blot: Mouse brain stained with ARG45783 anti-SARI antibody at 0.5 μg/ml dilution.
