Overview

Product Description	Rabbit Polyclonal antibody recognizes SAT1
Tested Reactivity	Hu
Tested Application	WB
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Target Name	SAT1
Antigen Species	Human
Immunogen	Recombinant protein of Human SAT1.
Conjugation	Un-conjugated
Alternate Names	SAT1; Spermidine/Spermine N1-Acetyltransferase 1; SSAT; SAT; Polyamine N-Acetyltransferase 1; Diamine N-Acetyltransferase 1; Putrescine Acetyltransferase; Diamine Acetyltransferase 1; EC 2.3.1.57; SSAT-1; Spermidine/Spermine N1-Acetyltransferase Alpha; Spermidine/Spermine N(1)-Acetyltransferase 1; Epididymis Secretory Sperm Binding Protein; Spermidine/Spermine N1-Acetyltransferase 2; KFSDX; DC21; KFSD

Application Instructions

Application Suggestion	Tested Application Dilution WB 1:500 - 1:2000
Application Note	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form	Liquid
Purification	Affinity chromatography purified
Buffer	0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol.
Preservative	0.01% Sodium azide
Stabilizer	30% Glycerol
Storage Instruction	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 6303 Human SAT1 Swiss-port # P21673 Human Diamine acetyltransferase 1
Gene Symbol	SAT1
Gene Full Name	Spermidine/Spermine N1-Acetyltransferase 1
Background	The protein encoded by this gene belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.[provided by RefSeq, Sep 2009]
Function	Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. [UniProt]
Cellular Localization	Cytoplasm; cytosol. [UniProt]
Calculated MW	20 kDa

Images (1) Click the Picture to Zoom In