ARG45771
anti-SCC112 antibody
anti-SCC112 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SCC112 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SCC112 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human SCC112. |
| Conjugation | Un-conjugated |
| Alternate Names | PDS5A; PDS5 Cohesin Associated Factor A; SCC-112; KIAA0648; PIG54; Sister Chromatid Cohesion Protein PDS5 Homolog A; Cell Proliferation-Inducing Gene 54 Protein; Sister Chromatid Cohesion Protein 112; PDS5, Regulator Of Cohesion Maintenance, Homolog A (S. Cerevisiae); PDS5, Regulator Of Cohesion Maintenance, Homolog A; SCC112; PDS5 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 151 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # A4L9P7 Rat Sister chromatid cohesion protein PDS5 homolog A Swiss-port # Q29RF7 Human Sister chromatid cohesion protein PDS5 homolog A |
|---|---|
| Gene Symbol | PDS5A |
| Gene Full Name | PDS5 Cohesin Associated Factor A |
| Background | The protein encoded by this gene binds to the cohesin complex and associates with chromatin through most of the cell cycle. The encoded protein may play a role in regulating sister chromatid cohesion during mitosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010] |
| Function | Probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 151 kDa |
| PTM | Acetylation; Phosphoprotein. [UniProt] |
Images (5) Click the Picture to Zoom In
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ARG45771 anti-SCC112 antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG45771 anti-SCC112 antibody at 5 μg/ml dilution.
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ARG45771 anti-SCC112 antibody WB image
Western blot: Hela stained with ARG45771 anti-SCC112 antibody at 0.5 μg/ml dilution.
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ARG45771 anti-SCC112 antibody FACS image
Flow Cytometry: A431 stained with ARG45771 anti-SCC112 antibody at 1 µg/10^6 cells dilution.
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ARG45771 anti-SCC112 antibody WB image
Western blot: Rat stomach stained with ARG45771 anti-SCC112 antibody at 0.5 μg/ml dilution.
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ARG45771 anti-SCC112 antibody WB image
Western blot: Mouse stomach stained with ARG45771 anti-SCC112 antibody at 0.5 μg/ml dilution.
