ARG45265
anti-SDE2 antibody
anti-SDE2 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Polyclonal antibody recognizes SDE2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SDE2 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human SDE2. |
| Conjugation | Un-conjugated |
| Alternate Names | SDE2; SDE2 Telomere Maintenance Homolog; C1orf55; Replication Stress Response Regulator SDE2; Splicing Regulator SDE2; FLJ35382; SDE2 Telomere Maintenance Homolog (S. Pombe); Chromosome 1 Open Reading Frame 55; UPF0667 Protein C1orf55; Protein SDE2 Homolog; DJ671D7.1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 54 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SDE2 |
| Gene Full Name | SDE2 Telomere Maintenance Homolog |
| Background | Enables damaged DNA binding activity. Involved in several processes, including cellular response to UV; mitotic G1 DNA damage checkpoint signaling; and protein ubiquitination. Located in several cellular components, including Golgi apparatus; cytosol; and nuclear speck. [provided by Alliance of Genome Resources, Nov 2024] |
| Function | Inhibits translesion DNA synthesis by preventing monoubiquitination of PCNA, this is necessary to counteract damage due to ultraviolet light-induced replication stress. [UniProt] |
| Cellular Localization | Cytoplasm; Nucleus. [UniProt] |
| Calculated MW | 50 kDa |
| PTM | Phosphoprotein; Ubl conjugation. [UniProt] |
Images (4) Click the Picture to Zoom In
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ARG45265 anti-SDE2 antibody IHC-P image
Immunohistochemistry: Human lung adenocarcinoma stained with ARG45265 anti-SDE2 antibody at 2 μg/ml dilution.
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ARG45265 anti-SDE2 antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG45265 anti-SDE2 antibody at 5 ug/ml dilution.
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ARG45265 anti-SDE2 antibody WB image
Western blot: K562 and HEL stained with ARG45265 anti-SDE2 antibody at 0.5 μg/ml dilution.
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ARG45265 anti-SDE2 antibody FACS image
Flow Cytometry: Jurkat stained with ARG45265 anti-SDE2 antibody at 1 µg/10^6 cells dilution.
