ARG45623
anti-SEL1L antibody
anti-SEL1L antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SEL1L |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SEL1L |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human SEL1L. |
| Conjugation | Un-conjugated |
| Alternate Names | SEL1L Adaptor Subunit Of SYVN1 Ubiquitin Ligase; PRO1063; SEL1L1; Sel-1L; Protein sel-1 homolog 1; SEL1-LIKE; Suppressor of lin-12-like protein 1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 100 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SEL1L |
| Gene Full Name | SEL1L Adaptor Subunit Of SYVN1 Ubiquitin Ligase |
| Background | The protein encoded by this gene is part of a protein complex required for the retrotranslocation or dislocation of misfolded proteins from the endoplasmic reticulum lumen to the cytosol, where they are degraded by the proteasome in a ubiquitin-dependent manner. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| Function | Plays a role in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. [UniProt] |
| Cellular Localization | Endoplasmic reticulum; Membrane. [UniProt] |
| Calculated MW | 89 kDa |
| PTM | N-glycosylated. [UniProt] |
Images (7) Click the Picture to Zoom In
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ARG45623 anti-SEL1L antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG45623 anti-SEL1L antibody at 5 μg/ml dilution.
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ARG45623 anti-SEL1L antibody WB image
Western blot: HepG2 stained with ARG45623 anti-SEL1L antibody at 0.5 μg/ml dilution.
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ARG45623 anti-SEL1L antibody FACS image
Flow Cytometry: HEL stained with ARG45623 anti-SEL1L antibody at 1 µg/10^6 cells dilution.
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ARG45623 anti-SEL1L antibody IHC-P image
Immunohistochemistry: Rat pancreas stained with ARG45623 anti-SEL1L antibody at 2 μg/ml dilution.
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ARG45623 anti-SEL1L antibody WB image
Western blot: Rat pancreas stained with ARG45623 anti-SEL1L antibody at 0.5 μg/ml dilution.
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ARG45623 anti-SEL1L antibody IHC-P image
Immunohistochemistry: Mouse pancreas stained with ARG45623 anti-SEL1L antibody at 2 μg/ml dilution.
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ARG45623 anti-SEL1L antibody WB image
Western blot: Mouse pancreas stained with ARG45623 anti-SEL1L antibody at 0.5 μg/ml dilution.
