ARG46467
anti-SGSM1 / RUTBC2 antibody
anti-SGSM1 / RUTBC2 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SGSM1 / RUTBC2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SGSM1 / RUTBC2 |
| Antigen Species | Human |
| Immunogen | A 17 amino acid synthetic peptide within the last 50 amino acids of human SGSM1 / RUTBC2. |
| Conjugation | Un-conjugated |
| Alternate Names | SGSM1; RUTBC2; KIAA1941; RUTBC2; Small G protein signaling modulator 1; RUN and TBC1 domain-containing protein 2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -517°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q2NKQ1 Human Small G protein signaling modulator 1 Swiss-port # Q8BPQ7 Mouse Small G protein signaling modulator 1 |
|---|---|
| Gene Symbol | SGSM1 |
| Gene Full Name | small G protein signaling modulator 1 |
| Background | Enables GTPase activator activity and small GTPase binding activity. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Located in cytoplasmic vesicle membrane and cytosol. [provided by Alliance of Genome Resources, Jul 2025] |
| Function | Interacts with numerous Rab family members, functioning as Rab effector for some, and as GTPase activator for others. Promotes GTP hydrolysis by RAB34 and RAB36. Probably functions as a GTPase effector with RAB9A and RAB9B; does not stimulate GTP hydrolysis with RAB9A and RAB9B. [UniProt] |
| Cellular Localization | Cytoplasm; Cytoplasmic vesicle; Cytoplasmic vesicle; Golgi apparatus. [UniProt] |
| Calculated MW | 130 kDa |
