ARG45472
anti-SGT1 / ECD antibody
anti-SGT1 / ECD antibody for Flow cytometry,ICC/IF,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SGT1 / ECD |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SGT1 / ECD |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human SGT1 / ECD. |
| Conjugation | Un-conjugated |
| Alternate Names | ECD; Ecdysoneless Cell Cycle Regulator; HSGT1; GCR2; Protein Ecdysoneless Homolog; Human Suppressor Of GCR Two; Ecdysoneless Homolog (Drosophila); Suppressor Of S. Cerevisiae Gcr2; Ecdysoneless Homolog; Suppressor Of GCR2; Protein SGT1; SGT1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 80 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | ECD |
| Gene Full Name | Ecdysoneless Cell Cycle Regulator |
| Background | Enables histone acetyltransferase binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Feb 2025] |
| Function | Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP. [UniProt] |
| Cellular Localization | Cytoplasm; Nucleus. [UniProt] |
| Calculated MW | 73 kDa |
| PTM | Phosphoprotein. [UniProt] |
Images (3) Click the Picture to Zoom In
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ARG45472 anti-SGT1 / ECD antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG45472 anti-SGT1 / ECD antibody at 5 μg/ml dilution.
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ARG45472 anti-SGT1 / ECD antibody WB image
Western blot: PC-3 stained with ARG45472 anti-SGT1 / ECD antibody at 0.5 μg/ml dilution.
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ARG45472 anti-SGT1 / ECD antibody FACS image
Flow Cytometry: K562 stained with ARG45472 anti-SGT1 / ECD antibody at 1 µg/10^6 cells dilution.
