anti-SIRT4 antibody

anti-SIRT4 antibody for ELISA,Western blot and Human,Mouse,Rat

Cell Biology and Cellular Response antibody; Gene Regulation antibody; Metabolism antibody; Signaling Transduction antibody


Product Description Chicken Polyclonal antibody recognizes SIRT4
Tested Reactivity Hu, Ms, Rat
Tested Application ELISA, WB
Host Chicken
Clonality Polyclonal
Isotype IgY
Target Name SIRT4
Immunogen Synthetic peptide (17 aa) within aa. 80-130 of Human SIRT4.
Conjugation Un-conjugated
Alternate Names SIR2L4; NAD-dependent ADP-ribosyltransferase sirtuin-4; NAD-dependent protein deacetylase sirtuin-4; SIR2-like protein 4; EC 3.5.1.-; NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; EC 2.4.2.-; Regulatory protein SIR2 homolog 4

Application Instructions

Application Suggestion
Tested Application Dilution
WB1 - 2 μg/mL
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Human Liver Tissue Lysate


Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS and 0.02% Sodium azide
Preservative 0.02% Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 23409 Human SIRT4

GeneID: 75387 Mouse SIRT4

Swiss-port # Q8R216 Mouse NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

Swiss-port # Q9Y6E7 Human NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

Gene Symbol SIRT4
Gene Full Name sirtuin 4
Background SIRT4 Antibody: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT4 localizes to mitochondria, inhibits glutamate dehydrogenase, and is thought to be involved in the regulation of insulin secretion. |
Research Area Cell Biology and Cellular Response antibody; Gene Regulation antibody; Metabolism antibody; Signaling Transduction antibody
Calculated MW 35 kDa

Images (1) Click the Picture to Zoom In

  • ARG54660 anti-SIRT4 antibody WB image

    Western blot: human liver tissue lysate stained with ARG54660 anti-SIRT4 antibody at 1 μg/ml.