ARG46494
anti-SLC29A2 / ENT2 antibody
anti-SLC29A2 / ENT2 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SLC29A2 / ENT2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SLC29A2 / ENT2 |
| Antigen Species | Human |
| Immunogen | A 19 amino acid synthetic peptide within the last 50 amino acids of human SLC29A2 / ENT2. |
| Conjugation | Un-conjugated |
| Alternate Names | SLC29A2; Solute carrier family 29 member 2; Nucleoside transporter, ei-type; 36 kDa nucleolar protein HNP36; DER12; Hydrophobic nucleolar protein, 36 kDa; Delayed-early response protein 12; Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter; ENT2; Equilibrative NBMPR-insensitive nucleoside transporter; Equilibrative nucleoside transporter 2; HNP36 |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 50 kDa |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q14542 Human Equilibrative nucleoside transporter 2 |
|---|---|
| Gene Symbol | SLC29A2 |
| Gene Full Name | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| Background | The uptake of nucleosides by transporters, such as SLC29A2, is essential for nucleotide synthesis by salvage pathways in cells that lack de novo biosynthetic pathways. Nucleoside transport also plays a key role in the regulation of many physiologic processes through its effect on adenosine concentration at the cell surface (Griffiths et al., 1997 [PubMed 9396714]).[supplied by OMIM, Nov 2008] |
| Function | Mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine. Very less sensitive than SLC29A1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyridamole, dilazep and draflazine. [UniProt] |
| Cellular Localization | Basolateral cell membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Note=Localized at the basolateral cell membrane in polarized MDCK cells. [UniProt] |
| Calculated MW | 50 kDa |
Images (2) Click the Picture to Zoom In
-
ARG46494 anti-SLC29A2 / ENT2 antibody IHC-P image
Immunohistochemistry: Human bladder stained with ARG46494 anti-SLC29A2 / ENT2 antibody.
-
ARG46494 anti-SLC29A2 / ENT2 antibody WB image
Western blot: Human bladder stained with ARG46494 anti-SLC29A2 / ENT2 antibody.
