ARG46498
anti-SLC35D2 / HFRC antibody
anti-SLC35D2 / HFRC antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SLC35D2 / HFRC |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SLC35D2 / HFRC |
| Antigen Species | Human |
| Immunogen | A 14 amino acid synthetic peptide within the last 50 amino acids of human SLC35D2 / HFRC. |
| Conjugation | Un-conjugated |
| Alternate Names | solute carrier family 35, member D2; SLC35D2; hfrc; HFRC1; SQV7L; UGTrel8; HFRC; UGTREL8; Homolog of Fringe connection protein 1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -548°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q76EJ3 Human UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter |
|---|---|
| Gene Symbol | SLC35D2 |
| Gene Full Name | solute carrier family 35, member D2 |
| Background | Nucleotide sugars, which are synthesized in the cytosol or the nucleus, are high-energy donor substrates for glycosyltransferases located in the lumen of the endoplasmic reticulum and Golgi apparatus. Translocation of nucleotide sugars from the cytosol into the lumen compartment is mediated by specific nucleotide sugar transporters, such as SLC35D2 (Suda et al., 2004 [PubMed 15082721]).[supplied by OMIM, Mar 2008] |
| Function | Nucleotide sugar antiporter transporting UDP-N-acetylglucosamine (UDP-GlcNAc) and UDP-glucose (UDP-Glc) from the cytosol into the lumen of the Golgi in exchange of UMP. By supplying UDP-N-acetylglucosamine, a donor substrate to heparan sulfate synthases, probably takes part in the synthesis of these glycoconjugates. [UniProt] |
| Cellular Localization | Golgi apparatus. [UniProt] |
| Calculated MW | 37 kDa |
