ARG45595
anti-SMC2 antibody
anti-SMC2 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SMC2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SMC2 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human SMC2. |
| Conjugation | Un-conjugated |
| Alternate Names | SMC2; Structural Maintenance Of Chromosomes 2; SMC2; Structural Maintenance Of Chromosomes 2; HCAP-E; SMC2L1; CAP-E; SMC2 (Structural Maintenance Of Chromosomes 2, Yeast)-Like 1; Structural Maintenance Of Chromosomes Protein 2; Chromosome-Associated Protein E; XCAP-E Homolog; SMC Protein 2; SMC-2; CAPE; Structural Maintenance Of Chromosomes (SMC) Family Member, Chromosome-Associated Protein E; SMC2 Structural Maintenance Of Chromosomes 2-Like 1 (Yeast) |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 136 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O95347 Human Structural maintenance of chromosomes protein 2 Swiss-port # Q8CG48 Mouse Structural maintenance of chromosomes protein 2 |
|---|---|
| Gene Symbol | SMC2 |
| Gene Full Name | Structural Maintenance Of Chromosomes 2 |
| Background | Predicted to enable ATP binding activity; chromatin binding activity; and single-stranded DNA binding activity. Involved in mitotic chromosome condensation. Located in condensed chromosome; cytoplasm; and nuclear lumen. Part of condensin complex. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. [UniProt] |
| Cellular Localization | Chromosome, Cytoplasm, Nucleus. [UniProt] |
| Calculated MW | 136 kDa |
| PTM | Acetylation. [UniProt] |
Images (5) Click the Picture to Zoom In
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ARG45595 anti-SMC2 antibody ICC/IF image
Immunofluorescence: A549 stained with ARG45595 anti-SMC2 antibody at 5 μg/ml dilution.
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ARG45595 anti-SMC2 antibody WB image
Western blot: 293T stained with ARG45595 anti-SMC2 antibody at 0.5 μg/ml dilution.
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ARG45595 anti-SMC2 antibody FACS image
Flow Cytometry: 293T stained with ARG45595 anti-SMC2 antibody at 1 µg/10^6 cells dilution.
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ARG45595 anti-SMC2 antibody WB image
Western blot: C6 stained with ARG45595 anti-SMC2 antibody at 0.5 μg/ml dilution.
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ARG45595 anti-SMC2 antibody WB image
Western blot: NIH/3T3 stained with ARG45595 anti-SMC2 antibody at 0.5 μg/ml dilution.
