anti-SOAT2 / ACAT2 antibody

anti-SOAT2 / ACAT2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Pig,Rat,Sheep

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Product Description Rabbit Polyclonal antibody recognizes SOAT2 / ACAT2
Tested Reactivity Hu, Ms, Rat, Pig, Sheep
Tested Application ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name SOAT2 / ACAT2
Antigen Species Human
Immunogen Synthetic peptide around the N-terminus of Human SOAT2 / ACAT2.
Conjugation Un-conjugated
Alternate Names Cholesterol acyltransferase 2; ACACT2; ACAT-2; Sterol O-acyltransferase 2; ACAT2; ARGP2; Acyl-coenzyme A:cholesterol acyltransferase 2; EC

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:200 - 1:500
IHC-P1:200 - 1:500
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Affinity purification with immunogen.
Buffer TBS (pH 7.4), 0.02% Sodium azide, 50% Glycerol and 0.1% BSA.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol and 0.1% BSA
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 223920 Mouse SOAT2

GeneID: 266770 Rat SOAT2

GeneID: 8435 Human SOAT2

Gene Symbol SOAT2
Gene Full Name sterol O-acyltransferase 2
Background Summary:This gene is a member of a small family of acyl coenzyme A:cholesterol acyltransferases. The gene encodes a membrane-bound enzyme localized in the endoplasmic reticulum that produces intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. The cholesterol esters are then stored as cytoplasmic lipid droplets inside the cell. The enzyme is implicated in cholesterol absorption in the intestine and in the assembly and secretion of apolipoprotein B-containing lipoproteins such as very low density lipoprotein (VLDL). Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008]
Function Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa. [UniProt]
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Calculated MW 60 kDa

Images (1) Click the Picture to Zoom In

  • ARG57814 anti-SOAT2 / ACAT2 antibody WB image

    Western blot: 30 µg of Mouse liver, 30 µg of JGC-1, 30 µg of Jurkat and 60 µg of Rat liver lysates stained with ARG57814 anti-SOAT2 / ACAT2 antibody.

Specific References

Sterol O-acyltransferase 2 chaperoned by apolipoprotein J facilitates hepatic lipid accumulation following viral and nutrient stresses.

WB / Human

Hung-Yu Sun et al.
Commun Biol.,  (2021)