ARG46211
anti-SP110 antibody
anti-SP110 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SP110 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SP110 |
| Antigen Species | Human |
| Immunogen | A 15 amino acid synthetic peptide within aa. 470 - 520 of human SP110. |
| Conjugation | Un-conjugated |
| Alternate Names | SP110; Transcriptional coactivator Sp110; VODI; Sp110 nuclear body protein; Speckled 110 kDa; IPR1; Interferon-induced protein 41/75; IFI75; IFI41 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SP110 |
| Gene Full Name | SP110 nuclear body protein |
| Background | The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Jul 2008] |
| Function | Transcription factor. May be a nuclear hormone receptor coactivator. Enhances transcription of genes with retinoic acid response elements (RARE). [UniProt] |
| Cellular Localization | Nucleus. Note=Found in the nuclear body. [UniProt] |
| Calculated MW | 78 kDa |
| PTM | Phosphorylated (isoform 2). [UniProt] |
Images (3) Click the Picture to Zoom In
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ARG46211 anti-SP110 antibody IHC-P image
Immunohistochemistry: Human brain stained with ARG46211 anti-SP110 antibody.
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ARG46211 anti-SP110 antibody ICC/IF image
Immunofluorescence: Human brain stained with ARG46211 anti-SP110 antibody.
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ARG46211 anti-SP110 antibody WB image
Western blot: Hela stained with ARG46211 anti-SP110 antibody.
