ARG45717

anti-SRP54 antibody

anti-SRP54 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes SRP54
Tested Reactivity Hu, Ms, Rat
Tested Application FACS, ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name SRP54
Antigen Species Human
Immunogen Recombinant protein containing to human SRP54.
Conjugation Un-conjugated
Alternate Names SRP54; Signal Recognition Particle 54; Signal Recognition Particle 54 KDa Protein; Signal Recognition Particle Subunit SRP54; Signal Recognition Particle 54kDa; Signal Recognition Particle 54kD; EC 3.6.5.4; SCN8

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1 - 3 µg/10^6 cells
ICC/IF5 μg/ml
WB0.1-0.25 μg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purified
Buffer 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
Stabilizer 4% Trehalose
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 6729 Human SRP54

Swiss-port # P61011 Human Signal recognition particle 54 kDa protein

Gene Symbol SRP54
Gene Full Name Signal Recognition Particle 54
Background Enables several functions, including 7S RNA binding activity; endoplasmic reticulum signal peptide binding activity; and guanyl ribonucleotide binding activity. Contributes to GTPase activity. Involved in granulocyte differentiation and protein targeting to ER. Located in cytosol and nucleus. Part of signal recognition particle, endoplasmic reticulum targeting. Implicated in severe congenital neutropenia 8. [provided by Alliance of Genome Resources, Feb 2025]
Function Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). [UniProt]
Cellular Localization Cytoplasm; Endoplasmic reticulum; Nucleus; Signal recognition particle. [UniProt]
Calculated MW 56 kDa

Images (5) Click the Picture to Zoom In

  • ARG45717 anti-SRP54 antibody ICC/IF image

    Immunofluorescence: T47D stained with ARG45717 anti-SRP54 antibody at 5 μg/ml dilution.

  • ARG45717 anti-SRP54 antibody WB image

    Western blot: Hela stained with ARG45717 anti-SRP54 antibody at 0.5 μg/ml dilution.

  • ARG45717 anti-SRP54 antibody FACS image

    Flow Cytometry: U937 stained with ARG45717 anti-SRP54 antibody at 1 µg/10^6 cells dilution.

  • ARG45717 anti-SRP54 antibody WB image

    Western blot: C6 stained with ARG45717 anti-SRP54 antibody at 0.5 μg/ml dilution.

  • ARG45717 anti-SRP54 antibody WB image

    Western blot: NIH/3T3 stained with ARG45717 anti-SRP54 antibody at 0.5 μg/ml dilution.