ARG45796
anti-STXBP2 antibody
anti-STXBP2 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes STXBP2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | STXBP2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to N-terminal region of human STXBP2. |
| Conjugation | Un-conjugated |
| Alternate Names | STXBP2; syntaxin binding protein 2; Protein unc-18 homolog B; UNC18-2; Unc-18B; MUNC18-2; Unc18-2; Protein unc-18 homolog 2; UNC18B; FHL5; pp10122; Hunc18b; Syntaxin-binding protein 2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 66 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | STXBP2 |
| Gene Full Name | syntaxin binding protein 2 |
| Background | This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2013] |
| Function | Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells. [UniProt] |
| Cellular Localization | Azurophil granule; Cytolytic granule; Cytosol; Extracellular region; Plasma membrane; Presynapse. [UniProt] |
| Calculated MW | 66 kDa |
Images (5) Click the Picture to Zoom In
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ARG45796 anti-STXBP2 antibody ICC/IF image
Immunofluorescence: SK-OV-3 stained with ARG45796 anti-STXBP2 antibody at 5 μg/ml dilution.
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ARG45796 anti-STXBP2 antibody WB image
Western blot: K562 stained with ARG45796 anti-STXBP2 antibody at 0.5 μg/ml dilution.
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ARG45796 anti-STXBP2 antibody FACS image
Flow Cytometry: U937 stained with ARG45796 anti-STXBP2 antibody at 1 µg/10^6 cells dilution.
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ARG45796 anti-STXBP2 antibody WB image
Western blot: Rat brain stained with ARG45796 anti-STXBP2 antibody at 0.5 μg/ml dilution.
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ARG45796 anti-STXBP2 antibody WB image
Western blot: Mouse brain stained with ARG45796 anti-STXBP2 antibody at 0.5 μg/ml dilution.
