ARG54576

anti-Secretogranin II antibody

anti-Secretogranin II antibody for Immunohistochemistry,Immunoprecipitation,Western blot and Human,Rat

Neuroscience antibody

Overview

Product Description

Rabbit Polyclonal antibody recognizes Secretogranin II

Tested Reactivity Hu, Rat
Tested Application IHC, IP, WB
Specificity This antibody reacts specically with rat and human secretogranin II.
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Secretogranin II
Antigen Species Human
Immunogen N-terminal sequence (amino acids 1-19) of rat/human secretogranin II coupled to ovalbumin.
Conjugation Un-conjugated
Alternate Names EM66; Secretogranin II; CHGC; SgII; SN; Secretogranin-2; Chromogranin-C

Application Instructions

Application Note This antibody has been used successfully in Western blot assays (1:2,500 - 1:10,000 dilution) and immuno precipitation of secretogranin II (1:100 - 1:500 dilution), as well as in immunohistochemical identi cation of secretogranin II (1:1,000 dilution).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 24765 Rat SCG2

GeneID: 7857 Human SCG2

Swiss-port # P10362 Rat Secretogranin-2

Swiss-port # P13521 Human Secretogranin-2

Gene Symbol SCG2
Gene Full Name secretogranin II
Background The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown. [provided by RefSeq, Jul 2008]
Function Secretogranin-2 is a neuroendocrine secretory granule protein, which is the precursor for biologically active peptides. [UniProt]
Research Area Neuroscience antibody
Calculated MW 71 kDa
PTM O-glycosylated.